Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 11/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110688 | 0.91 | MAPT (0.58) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13110690 | 0.90 | AGPAT2 (0.57) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13127078 | 0.90 | AGPAT2 (0.57) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13110689 | 0.89 | AGPAT2 (0.65) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13110698 | 0.88 | MAPT (0.56) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13110691 | 0.86 | AGPAT2 (0.55) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13111043 | 0.86 | AGPAT2 (0.53) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13110706 | 0.83 | RAB9A (0.64) | AGPAT2MAPTTP53ALOX15KMT2A | |
| SCHEMBL13110704 | 0.80 | AGPAT2 (0.65) | AGPAT2MAPTTP53HPGDALOX15 | |
| SCHEMBL13880180 | 0.80 | AGPAT2 (0.88) | AGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820654-B2 | Pyrimidine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-10-26 | — | — | US | disclosed |
| US-7820654-B2 | Pyrimidine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-10-26 | — | — | US | disclosed |