SCHEMBL1311092

SCHEMBL1311092

F[CH]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754978 1.00 KDM4E (0.32) KDM4ETSHRTDP1
SCHEMBL9496803 1.00 KDM4E (0.32) KDM4ETSHRTDP1
SCHEMBL9493877 0.97 KDM4E (0.33) KDM4ETSHRTDP1
SCHEMBL9498507 0.89 KDM4E (0.34) KDM4ETSHRTDP1
SCHEMBL5489726 0.80 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL5487202 0.80 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL1827978 0.80 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL1824897 0.80 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL1824498 0.80 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL5056143 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1385914-A1 DICHROIC MIXTURE Rolic AG (CH) 2004-02-04 EP claimed
WO-2002090447-A1 DICHROIC MIXTURE ROLIC AG (CH) 2002-11-14 WO claimed
CN-111948846-B Polymer dispersed liquid crystal element and liquid crystal composition for polymer dispersed liquid crystal element DIC株式会社 2023-11-28 CN disclosed
CN-113088101-B Polymerizable dichroic dyes 罗利克技术有限公司 2023-07-04 CN disclosed
CN-111948846-A Polymer dispersed liquid crystal element and liquid crystal composition for polymer dispersed liquid crystal element DIC株式会社 2020-11-17 CN disclosed
CN-107209309-B Polymerizable composition and optically anisotropic body using the same DIC株式会社 2020-06-02 CN disclosed
CN-107209307-B Polymerizable composition and optically anisotropic body using same DIC株式会社 2020-04-28 CN disclosed
CN-111051934-A Light conversion film and image display element using same DIC株式会社 2020-04-21 CN disclosed
CN-107108775-B Polymerizable composition and optically anisotropic body using the same DIC株式会社 2019-12-13 CN disclosed
CN-107108770-B Polymerizable composition and optically anisotropic body using the same DIC株式会社 2019-12-13 CN disclosed
US-10202470-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2019-02-12 US disclosed
US-20060063902-A1 Transparent fluorine-containing copolymer CENTRAL GLASS CO., LTD. (JP) 2006-03-23 US disclosed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 US disclosed
EP-1385914-A1 DICHROIC MIXTURE Rolic AG (CH) 2004-02-04 EP disclosed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 EP disclosed
EP-1261659-A1 PHOTOACTIVE POLYIMIDES, POLYAMIDE ACIDS OR ESTERS WITH SIDE CHAIN PHOTOCROSSLINKABLE GROUPS Rolic AG (CH) 2002-12-04 EP disclosed
WO-2002090447-A1 DICHROIC MIXTURE ROLIC AG (CH) 2002-11-14 WO disclosed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO disclosed
US-6340506-B1 USED AS ORIENTATION LAYERS FOR LIQUID CRYSTALS, OPTICS ROLIC AG (CH) 2002-01-22 US disclosed
WO-2001053384-A1 PHOTOACTIVE POLYIMIDES, POLYAMIDE ACIDS OR ESTERS WITH SIDE CHAIN PHOTOCROSSLINKABLE GROUPS ROLIC AG (CH) 2001-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked C9, F12, DAO KDM4E 1781/4885TSHR 4654/4885TDP1 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.