Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15460822 | 0.90 | — | — | |
| SCHEMBL8771423 | 0.90 | CYP2C9 (0.36) | CYP2C9CYP3A4MAPTGAAALDH1A1 | |
| SCHEMBL8771419 | 0.90 | CYP2C9 (0.36) | CYP2C9CYP3A4MAPTGAAALDH1A1 | |
| SCHEMBL8730440 | 0.88 | MEN1 (0.32) | MAPTGAAMEN1KMT2A | |
| SCHEMBL15460813 | 0.87 | CYP3A4 (0.32) | CYP2C9CYP3A4 | |
| SCHEMBL13198625 | 0.86 | MEN1 (0.31) | CYP2C9MAPTGAAALDH1A1LMNA | |
| SCHEMBL10017839 | 0.86 | MEN1 (0.31) | CYP2C9MAPTGAAALDH1A1LMNA | |
| SCHEMBL15460871 | 0.85 | — | — | |
| SCHEMBL13198626 | 0.84 | CYP2C9 (0.38) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL20111087 | 0.84 | MAPT (0.33) | CYP2C9CYP3A4FASNMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807236-B2 | At least two liquid crystalline compounds one of which contains a 3-fluoro-4-(2,2-difluorovinyl)phenyl group; twisted or supertwisted nematic, in plane-aligned, or matrix liquid crystal displays; mobile applications | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |