SCHEMBL8771419

SCHEMBL8771419

CCCCC[C@H]1CC[C@H](c2ccc(-c3cc(F)c(OC=C(F)F)c(F)c3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
SPHK1 Q9NYA1 5/20 0.33
GAA P10253 1/20 0.33
ESR2 Q92731 1/20 0.33
S1PR1 P21453 5/20 0.32
DGAT1 O75907 1/20 0.32
SGPL1 O95470 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
S1PR4 O95977 1/20 0.32
S1PR5 Q9H228 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
S1PR3 Q99500 1/20 0.32
SPHK2 Q9NRA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771423 1.00 CYP2C9 (0.36) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL8771324 0.92 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL8771332 0.92 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL13112233 0.90 CYP2C9 (0.33) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL15460791 0.88 ALDH1A1 (0.32) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL15460621 0.88 SPHK1 (0.41) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL15460793 0.87 CYP2C9 (0.30) CYP2C9
SCHEMBL8730440 0.87 MEN1 (0.32) MAPTMEN1KMT2AGAA
SCHEMBL13198625 0.86 MEN1 (0.31) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10017839 0.86 MEN1 (0.31) CYP2C9MAPTALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799878-A1 Liquid crystal compositions and liquid crystal display elements containing same Shin-Etsu Chemical Co., Ltd. (JP) 1997-10-08 EP disclosed