Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PRKCA | P17252 | 4/20 | 0.60 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.60 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13112571 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112701 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112602 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112600 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112603 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112591 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112690 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112575 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112686 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 | |
| SCHEMBL13112576 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNALPAR3LPAR1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820803-B2 | Immobilized phosphatidic acid probe | Holmes, Andrew Bruce (GB) | 2010-10-26 | — | — | US | disclosed |