Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117656 | 0.93 | DGAT1 (0.45) | DGAT1SOAT1 | |
| SCHEMBL661514 | 0.81 | DGAT1 (0.59) | DGAT1 | |
| SCHEMBL13117866 | 0.76 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL10185472 | 0.75 | HPGD (0.51) | DGAT1 | |
| SCHEMBL10185715 | 0.75 | DGAT1 (0.49) | DGAT1SOAT1 | |
| SCHEMBL10184517 | 0.75 | DGAT1 (0.49) | DGAT1SOAT1 | |
| SCHEMBL10186181 | 0.73 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL16527560 | 0.71 | IDO1 (0.60) | DGAT1 | |
| SCHEMBL16542660 | 0.71 | IDO1 (0.60) | DGAT1 | |
| SCHEMBL13117661 | 0.71 | DGAT1 (0.37) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |