Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 10/20 | 0.48 |
| ▸ | TSLP | Q969D9 | 3/20 | 0.47 |
| ▸ | MC3R | P41968 | 3/20 | 0.47 |
| ▸ | MC1R | Q01726 | 3/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12706701 | 1.00 | MEN1 (0.50) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL12971683 | 0.92 | MEN1 (0.58) | MEN1KMT2AMC4RMC3RMC1R | |
| SCHEMBL13478113 | 0.92 | KLKB1 (0.48) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL13478174 | 0.92 | KLKB1 (0.48) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL12971678 | 0.92 | MEN1 (0.57) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL12971639 | 0.92 | MEN1 (0.57) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL13121224 | 0.92 | MEN1 (0.57) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL14401701 | 0.92 | MEN1 (0.57) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL14401768 | 0.92 | MEN1 (0.57) | MEN1KMT2AMC4RTSLPMC3R | |
| SCHEMBL12728013 | 0.92 | MEN1 (0.57) | MEN1KMT2AMC4RTSLPMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267639-A1 | TREATMENT OF OSTEOARTHRITIS | PROMICS PTY LIMITED (AU) | 2010-10-21 | — | — | US | disclosed |
| US-20100267639-A1 | TREATMENT OF OSTEOARTHRITIS | PROMICS PTY LIMITED (AU) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267639-A1 | TREATMENT OF OSTEOARTHRITIS | C5AR2, C5AR1, C3AR1 | MEN1 3074/4885KMT2A 3986/4885MC4R 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.