Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MC4R | P32245 | 3/20 | 0.46 |
| ▸ | MC3R | P41968 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSLP | Q969D9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478174 | 1.00 | KLKB1 (0.48) | KLKB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12706701 | 0.92 | MEN1 (0.50) | KLKB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13121327 | 0.92 | MEN1 (0.50) | KLKB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12971683 | 0.89 | MEN1 (0.58) | F12MEN1MC4RMC3RKMT2A | |
| SCHEMBL23318097 | 0.89 | HDAC3 (0.49) | KLKB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12971708 | 0.89 | HDAC3 (0.49) | KLKB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13121298 | 0.89 | HDAC3 (0.49) | KLKB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12728131 | 0.89 | HDAC3 (0.49) | KLKB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14401768 | 0.89 | MEN1 (0.57) | MEN1MC4RMC3RKMT2ATSLP | |
| SCHEMBL12728013 | 0.89 | MEN1 (0.57) | MEN1MC4RMC3RKMT2ATSLP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659246-B2 | Treatment of osteoarthritis | PROMICS PTY LIMITED (AU) | 2010-02-09 | — | — | US | disclosed |