SCHEMBL13122853

SCHEMBL13122853

OC[C@H]1O[C@@H](Oc2cccc3nnn(CCc4ccc5c(c4)CCO5)c23)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.75

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 17/20 0.75
▸ SLC5A1 P13866 12/20 0.75
▸ SLC28A3 Q9HAS3 1/20 0.38
▸ ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13122858 0.89 SLC5A2 (0.65) SLC5A2SLC5A1
SCHEMBL3412682 0.86 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL3410762 0.86 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL13107690 0.85 SLC5A2 (1.00) SLC5A2SLC5A1SLC28A3
SCHEMBL3412686 0.84 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL3410769 0.84 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL3410768 0.84 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL4416370 0.84 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL13107696 0.81 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL3410749 0.77 SLC5A2 (0.51) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816330-B2 Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides JANSSEN PHARMACEUTICA NV (BE) 2010-10-19 — — US disclosed
US-20100004188-A1 SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES URBANSKI MAUD 2010-01-07 — — US disclosed
US-20090105165-A1 SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES URBANSKI MAUD 2009-04-23 — — US disclosed
US-7511020-B2 Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105165-A1 SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES GANAB, GCG, B3GAT3 SLC5A2 16/4885SLC5A1 18/4885SLC28A3 1699/4885
US-20100004188-A1 SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES GANAB, GCG, GANC SLC5A2 18/4885SLC5A1 19/4885SLC28A3 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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