Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312360 | 1.00 | HSD17B10 (0.53) | HSD17B10SMN1; SMN2NPC1ALDH1A1CHRM2 | |
| SCHEMBL1312361 | 1.00 | HSD17B10 (0.53) | HSD17B10SMN1; SMN2NPC1ALDH1A1CHRM2 | |
| SCHEMBL2024759 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL694279 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL694281 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL201852 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL199927 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL5579709 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL694280 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL375241 | 0.92 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851568-B | Synthetic method of 3-hydroxy-2-piperidinecarboxylic acid compound and hydrochloride thereof | 五邑大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-112851568-A | Synthetic method of 3-hydroxy-2-piperidinecarboxylic acid compound and hydrochloride thereof | 五邑大学 | 2021-05-28 | — | — | CN | disclosed |
| WO-2016056031-A1 | NOVEL DIOL COMPOUNDS SYNTHESIS AND ITS USE FOR FORMAL SYNTHESIS OF (2R, 3 S)-3-HYDROXYPIPECOLIC ACID | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-04-14 | — | — | WO | disclosed |
| US-20110275673-A1 | INHIBITORS OF SPHINGOSINE KINASE 1 | GENZYME CORPORATION | 2011-11-10 | — | — | US | disclosed |
| WO-2010033701-A2 | INHIBITORS OF SPHINGOSINE KINASE 1 | GENZYME CORPORATION (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275673-A1 | INHIBITORS OF SPHINGOSINE KINASE 1 | SPHK1, SPHK2, S1PR1 | HSD17B10 914/4885SMN1; SMN2 1693/4885NPC1 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.