SCHEMBL199927

SCHEMBL199927

CC(C)(C)OC(=O)N1CCC(O)[C@H]1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.47
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.40
PREP P48147 2/20 0.39
USP2 O75604 1/20 0.39
GPR119 Q8TDV5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18544098 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL694280 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL2024759 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL694279 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL375241 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL5579709 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL694281 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL201852 1.00 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL4002727 0.92 HSD17B10 (0.42) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL1312359 0.92 HSD17B10 (0.53) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 939 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011119-A Preparation method and application of bionic collagen cyclohexapeptide 成都欣肽生物科技有限公司 2026-05-12 CN claimed
WO-2025124444-A1 USE OF HYDROXYPROLINE AND DERIVATIVE THEREOF, BIOLOGICAL HERBICIDE, BROAD-SPECTRUM HERBICIDE, AND WEED CONTROL METHOD 三亚市国家耐盐碱水稻技术创新中心 2025-06-19 WO claimed
CN-120130489-A Application of hydroxyproline and derivatives thereof, biological herbicide, broad-spectrum herbicide and weed control method 三亚市国家耐盐碱水稻技术创新中心 2025-06-13 CN claimed
CN-119019539-A Iterative index synthesis method of long-chain collagen-like polypeptide 上海欣肽生物科技有限公司 2024-11-26 CN claimed
CN-118684615-A Synthesis method of difluoro cyclobutane proline and derivative thereof 吉尔多肽生物制药(大连市)有限公司 2024-09-24 CN claimed
CN-114573562-B Niacin-containing triazole compound and preparation method and application thereof 西安交通大学 2023-07-07 CN claimed
CN-114573567-B Indazole cyclotriazole compound and preparation method and application thereof 西安交通大学 2023-05-02 CN claimed
CN-114437113-B Thiazolopyridine cyclotriazole compound, and preparation method and application thereof 西安交通大学 2023-05-02 CN claimed
CN-114437037-B Compound containing pyridine-bis-triazole as well as preparation method and application thereof 西安交通大学 2023-04-07 CN claimed
CN-110724138-B Synthesis method of (2S) -4-oxo-2- (3-thiazolidinyl carbonyl) -1-pyrrolidine carboxylic acid tert-butyl ester 山东邹平大展新材料有限公司 2022-11-22 CN claimed
CN-111378007-A Method for preparing palippivir by using second-generation Hoveyda-Grubbs catalyst 杭州勇诚睿生物科技有限公司 2020-07-07 CN claimed
CN-109796439-B Hydroxyproline peptide derivative and preparation method and application thereof 西安交通大学 2020-05-19 CN claimed
CN-109761957-B Hydroxyproline-containing compound and preparation method and application thereof 西安交通大学 2020-05-19 CN claimed
CN-110724138-A Synthesis method of (2S) -4-oxo-2- (3-thiazolidinyl carbonyl) -1-pyrrolidine carboxylic acid tert-butyl ester 山东邹平大展新材料有限公司 2020-01-24 CN claimed
CN-106256819-A A kind of synthetic method of (4S) N Boc 4 methoxy L proline amine salt 重庆博腾制药科技股份有限公司 2016-12-28 CN claimed
CN-105801462-A Synthesis method of (4S) -N-Boc-4-methoxymethyl-L-proline 重庆博腾制药科技股份有限公司 2016-07-27 CN claimed
CN-101695670-A Catalysts for Baylis-Hillman reaction and preparation method thereof NANJING UNIVERSITY OF TECHNOLOGY 2010-04-21 CN claimed
EP-2160392-A2 NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION Intermune, Inc. (US) 2010-03-10 EP claimed
US-20090155209-A1 NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION INTERMUNE, INC. 2009-06-18 US claimed
WO-2008137779-A2 NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION INTERMUNE, INC. (US) 2008-11-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155209-A1 NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION EIF2AK2, HAVCR2, HCCS HSD17B10 1531/4885CHRM2 4773/4885CHRM1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.