Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339343 | 0.80 | KMT2A (0.89) | KMT2AMAPTALDH1A1MMP2MMP9 | |
| SCHEMBL4311399 | 0.79 | KMT2A (0.63) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5698593 | 0.75 | KMT2A (1.00) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7799104 | 0.71 | KMT2A (0.72) | KMT2A | |
| SCHEMBL18449581 | 0.68 | APP (0.60) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL223767 | 0.67 | MAPT (0.65) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9057124 | 0.67 | KMT2A (0.40) | KMT2AMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29376197 | 0.67 | KMT2A (0.49) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4258701 | 0.67 | KMT2A (0.63) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| Methoxymethane SCHEMBL27637909 | 0.67 | HSD17B10 (0.67) | MAPTSMN1; SMN2ALDH1A1ACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790877-B2 | Antisense oligonucleotides with increased RNase sensitivity | GEN-PROBE, INCORPORATED (US) | 2010-09-07 | — | — | US | disclosed |