Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.64 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339343 | 0.94 | KMT2A (0.89) | KMT2APTGS2MAPK13MAPK12MAPK11 | |
| SCHEMBL11752008 | 0.84 | KMT2A (0.72) | KMT2APTGS2MEN1MAPTALDH1A1 | |
| SCHEMBL14670971 | 0.84 | KMT2A (0.72) | KMT2APTGS2MEN1MAPTALDH1A1 | |
| SCHEMBL11749411 | 0.84 | KMT2A (0.72) | KMT2APTGS2MEN1MAPTALDH1A1 | |
| SCHEMBL7799104 | 0.84 | KMT2A (0.72) | KMT2APTGS2PTGS1 | |
| SCHEMBL11753888 | 0.83 | KMT2A (0.71) | KMT2APTGS2MEN1MAPTALDH1A1 | |
| SCHEMBL11752848 | 0.83 | KMT2A (0.71) | KMT2APTGS2MEN1MAPTALDH1A1 | |
| SCHEMBL2091239 | 0.83 | MAPK13 (0.83) | KMT2APTGS2MAPK13MAPK12MAPK11 | |
| SCHEMBL4311399 | 0.78 | KMT2A (0.63) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11752556 | 0.77 | KMT2A (0.62) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510430-B | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-117510430-A | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-02-06 | — | — | CN | disclosed |
| EP-1682143-A2 | COMBINATIONS COMPRISING AN HSP90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | Pharmacia Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044194-A2 | TREATMENT OR PREVENTION OF NEOPLASIA BY USE OF AN Hsp90 INHIBITOR | PHARMACIA CORPORATION (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2005041879-A2 | COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | PHARMACIA CORPORATION (US) | 2005-05-12 | — | — | WO | disclosed |