Isoxazole

Isoxazole

SCHEMBL1312467

F.c1cnoc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoxazole SCHEMBL393230 0.96
Isoxazole SCHEMBL1318 0.96
Isoxazole SCHEMBL2679369 0.96 PARP1 (1.00)
Isoxazole SCHEMBL31018965 0.93
Isoxazole SCHEMBL21448373 0.93
Isoxazole SCHEMBL30791001 0.93
Isoxazole SCHEMBL2106061 0.93
Isoxazole SCHEMBL1118550 0.93
Isoxazole SCHEMBL9491120 0.93
Isoxazole SCHEMBL1798124 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452235-A Fluorine isoxazole class compound and preparation method thereof, pharmaceutical composition and purposes SHANGHAI INST MATERIA MEDICA CAS 2019-11-15 CN disclosed
CN-110452235-A Fluorine isoxazole class compound and preparation method thereof, pharmaceutical composition and purposes SHANGHAI INST MATERIA MEDICA CAS 2019-11-15 CN disclosed
CN-110452235-A Fluorine isoxazole class compound and preparation method thereof, pharmaceutical composition and purposes SHANGHAI INST MATERIA MEDICA CAS 2019-11-15 CN disclosed
CN-107108565-B The N- pyridine yl acetamide derivatives of inhibitor as WNT signal transmission approach 莱德克斯制药公共有限公司 2019-08-23 CN disclosed
CN-107108565-A The N pyridine yl acetamide derivatives of the inhibitor of approach are transmitted as WNT signals 莱德克斯制药公共有限公司 2017-08-29 CN disclosed
US-8642526-B2 Composition and method for recycling semiconductor wafers having low-k dielectric materials thereon ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2014-02-04 US disclosed
CN-102573458-A Monoalkyl sulfosuccinates in pesticide formulations and applications as hydrotropes AKZO NOBEL CHEMICALS INT BV 2012-07-11 CN disclosed
CN-102413695-A Safener for injury of penoxsulam herbicide in water-sown rice, direct-sown rice and transplanted rice DOW AGROSCIENCES LLC 2012-04-11 CN disclosed
US-20110275164-A1 COMPOSITION AND METHOD FOR RECYCLING SEMICONDUCTOR WAFERS HAVING LOW-K DIELECTRIC MATERIALS THEREON ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2011-11-10 US disclosed
US-7960328-B2 for removing low-k dielectric material, etch stop material, and/or metal stack material from rejected microelectronic device; hydrofluoric acid; pollution control, environment friendly ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2011-06-14 US disclosed
US-20100112728-A1 METHODS FOR STRIPPING MATERIAL FOR WAFER RECLAMATION ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2010-05-06 US disclosed
EP-1946358-A4 COMPOSITION AND METHOD FOR RECYCLING SEMICONDUCTOR WAFERS HAVING LOW-K DIELECTRIC MATERIALS THEREON ADVANCED TECH MATERIALS (US) 2009-03-04 EP disclosed
WO-2008157345-A2 WAFER RECLAMATION COMPOSITIONS AND METHODS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2008-12-24 WO disclosed
US-20080261847-A1 Composition and Method for Recycling Semiconductor Wafers Having Low-K Dielectric Materials Thereon ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2008-10-23 US disclosed
WO-2008121952-A1 METHODS FOR STRIPPING MATERIAL FOR WAFER RECLAMATION ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2008-10-09 WO disclosed
EP-1975987-A2 Methods for stripping material for wafer reclamation ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2008-10-01 EP disclosed
EP-1946358-A2 COMPOSITION AND METHOD FOR RECYCLING SEMICONDUCTOR WAFERS HAVING LOW-K DIELECTRIC MATERIALS THEREON ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2008-07-23 EP disclosed
WO-2007111694-A2 COMPOSITION AND METHOD FOR RECYCLING SEMICONDUCTOR WAFERS HAVING LOW-K DIELECTRIC MATERIALS THEREON ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2007-10-04 WO disclosed
CN-1206358-C DNA sequence of a gene of hydroxy-phenyl pyruvate dioxygenase and production of plants containing a gene of hydroxy-phenyl pyruvate dioxygenase and which are tolerant to certain herbicides RHONE POULENC AGROCHIMIE (FR) 2005-06-15 CN disclosed
CN-1192243-A DNA sequence of hydroxyphenyl pyruvate dioxygenase gene and obtaining of specific herbicide resistant plant containing hydroxyphenyl pyruvate dioxygenase gene RHONE POULENC AGROCHIMIE (FR) 1998-09-02 CN disclosed