Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26845462 | 0.95 | PRMT5 (0.34) | NPC1RAB9AUSP2MTORPRMT5 | |
| SCHEMBL13124537 | 0.93 | NPC1 (0.42) | NPC1RAB9AUSP2MTORPRMT5 | |
| SCHEMBL26845464 | 0.92 | MEN1 (0.33) | NPC1RAB9AUSP2PRMT5CARM1 | |
| SCHEMBL26845470 | 0.90 | KMT2A (0.42) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL13108258 | 0.89 | NPC1 (0.43) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL26845402 | 0.88 | PRMT5 (0.34) | PRMT5CARM1PRMT1 | |
| SCHEMBL26845542 | 0.86 | NPC1 (0.43) | NPC1RAB9AUSP2MTORPRMT5 | |
| SCHEMBL26845364 | 0.86 | NPC1 (0.37) | NPC1RAB9AUSP2MTORPRMT5 | |
| SCHEMBL26845388 | 0.85 | PRMT1 (0.40) | PRMT5CARM1PRMT1 | |
| SCHEMBL26845406 | 0.85 | PRMT1 (0.42) | NPC1RAB9AUSP2MTORPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940499-B2 | Reagent for blood analysis and method of use thereof | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2015-01-27 | — | — | US | disclosed |
| US-20100267080-A1 | REAGENT FOR BLOOD ANALYSIS AND METHOD OF USE THEREOF | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2010-10-21 | — | — | US | disclosed |
| US-7709653-B2 | Asymmetric cyanine compounds, their preparation methods and their uses | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO. LTD. (CN) | 2010-05-04 | — | — | US | disclosed |
| US-20090305285-A1 | ASYMMETRIC CYANINE COMPOUNDS, THEIR PREPARATION METHODS AND THEIR USES | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090305285-A1 | ASYMMETRIC CYANINE COMPOUNDS, THEIR PREPARATION METHODS AND THEIR USES | IK, RCN1, RCC1 | NPC1 2415/4885RAB9A 3144/4885USP2 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.