SCHEMBL1312504

SCHEMBL1312504

COC1(OC)C=CN=C(c2ccccn2)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.38
LMNA P02545 5/20 0.38
POLB P06746 3/20 0.38
CCR1 P32246 2/20 0.38
CCR5 P51681 2/20 0.38
CCR8 P51685 2/20 0.38
CYP1A2 P05177 1/20 0.38
METAP1 P53582 1/20 0.38
BLM P54132 1/20 0.38
HIF1A Q16665 1/20 0.38
DOHH Q9BU89 1/20 0.38
P4HTM Q9NXG6 1/20 0.38
TDP1 Q9NUW8 4/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TP53 P04637 4/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
HTT P42858 4/20 0.34
L3MBTL1 Q9Y468 4/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28149886 0.98 KDM4E (0.37) KDM4ELMNAPOLBCCR1CCR5
SCHEMBL9132752 0.98 KDM4E (0.37) KDM4ELMNAPOLBCCR1CCR5
Dipyridyl SCHEMBL29259897 0.98 KDM4E (0.41) KDM4ELMNAPOLBCCR1CCR5
SCHEMBL27609141 0.88 NPSR1 (0.37) KDM4ELMNAPOLBHIF1ATDP1
SCHEMBL435396 0.80 KDM4E (0.42) KDM4ELMNAPOLBCCR1CCR5
Hydrochloric Acid SCHEMBL38657196 0.78 KDM4E (0.41) KDM4ELMNAPOLBCCR1CCR5
SCHEMBL28575256 0.78 KDM4E (0.41) KDM4ELMNAPOLBCCR1CCR5
SCHEMBL28452296 0.77 KDM4E (0.39) KDM4ELMNAPOLBCCR1CCR5
SCHEMBL1311501 0.77 KDM4E (0.39) KDM4ELMNAPOLBCCR1CCR5
SCHEMBL7589592 0.76 KDM4E (0.42) KDM4ELMNAPOLBCCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117902966-B Synthesis method of aromatic aldehyde 中南大学 2026-05-12 CN claimed
CN-118908819-B Preparation method of organic ketone compound under synergistic catalysis of light and metal 延安大学 2025-04-18 CN claimed
CN-118908819-A Preparation method of organic ketone compound under synergistic catalysis of light and metal 延安大学 2024-11-08 CN claimed
CN-118047735-A Preparation method of pramoxine 中国人民解放军空军军医大学 2024-05-17 CN claimed
CN-117902966-A Synthesis method of aromatic aldehyde 中南大学 2024-04-19 CN claimed
CN-116589501-A Oxygen-bridged binuclear tungsten complex and preparation method and application thereof 江苏科技大学 2023-08-15 CN claimed
CN-116041198-A Method for synthesizing amide derivative by vanadium catalysis 陕西师范大学 2023-05-02 CN claimed
CN-114890856-A Method for synthesizing 2,2' -biphenyl-1-carboxylic acid derivative 华南理工大学 2022-08-12 CN claimed
CN-112250879-B Method for synthesizing ginkgo leaf polyprenol metal complex with light-operated activity 中国林业科学研究院林产化学工业研究所 2022-06-28 CN claimed
CN-112250879-A Method for synthesizing ginkgo leaf polyprenol metal complex with light-operated activity 中国林业科学研究院林产化学工业研究所 2021-01-22 CN claimed
CN-106748834-A A kind of method that the bipyridyl of 4,4 dimethoxy 2,2 silver catalytic hydrogenation aromatic nitro compound synthesizes arylamine 陕西师范大学 2017-05-31 CN claimed
CN-122079757-A 1, 2-Diacyl benzene compound and synthesis method and application thereof 2026-05-26 CN disclosed
US-20260132143-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF AMGEN INC. (US) 2026-05-14 US disclosed
CN-117902966-B Synthesis method of aromatic aldehyde 中南大学 2026-05-12 CN disclosed
CN-118908819-B Preparation method of organic ketone compound under synergistic catalysis of light and metal 延安大学 2025-04-18 CN disclosed
US-8268163-B2 Small volume in vitro analyte sensor and methods of making ABBOTT DIABETES CARE INC. (US) 2012-09-18 US disclosed
US-8262996-B2 Small volume in vitro sensor and methods of making ABBOTT DIABETES CARE INC. (US) 2012-09-11 US disclosed
US-8083924-B2 Small volume in vitro analyte sensor and methods of making ABBOTT DIABETES CARE INC. (US) 2011-12-27 US disclosed
US-20110275780-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMCIAL COMPANY LIMITED 2011-11-10 US disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132143-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF KRAS, NRAS, HRAS KDM4E 4400/4885LMNA 1584/4885POLB 2718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.