SCHEMBL13129155

SCHEMBL13129155

CCCCCCCCCCCCCC(=O)Nc1c(C(C)C)cc(Cc2cc(C(C)C)c(NC(=O)CCCC)c(C(C)C)c2)cc1C(C)C

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.47
HPGD P15428 2/20 0.45
MEN1 O00255 1/20 0.44
FAAH O00519 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14864153 0.99 SOAT1 (0.48) SOAT1HPGDMEN1FAAHMAPK1
SCHEMBL14864151 0.96 HPGD (0.47) SOAT1HPGDLMNAPOLBNPC1
SCHEMBL13129146 0.89 HPGD (0.45) SOAT1HPGDLMNAPOLBNPC1
SCHEMBL13129137 0.82 HPGD (0.58) HPGDKMT2ALMNAPOLBNPC1
SCHEMBL13129147 0.81 HPGD (0.48) SOAT1HPGDLMNAPOLBNPC1
SCHEMBL10699124 0.81 SOAT1 (0.69) SOAT1SMN1; SMN2
SCHEMBL14864149 0.81 HPGD (0.56) HPGDKMT2ALMNAPOLBNPC1
SCHEMBL14864150 0.80 HPGD (0.49) SOAT1HPGDLMNAPOLBNPC1
SCHEMBL13129141 0.78 HPGD (0.53) HPGDLMNAPOLBNPC1RAB9A
SCHEMBL13129134 0.77 HPGD (0.63) HPGDLMNAPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100240815-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-09-23 US disclosed