SCHEMBL14864150

SCHEMBL14864150

CCCCCCCCCCCCCC(=O)Nc1c(CC)cc(Cc2cc(CC)c(NC(=O)CCCCCCCCCCCCC)c(CC)c2)cc1CC

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.49
TRPV1 Q8NER1 1/20 0.47
ENPP2 Q13822 1/20 0.46
DGAT2 Q96PD7 1/20 0.46
LMNA P02545 2/20 0.44
POLB P06746 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CETP P11597 1/20 0.44
HSP90AA1 P07900 1/20 0.44
EPHX2 P34913 1/20 0.44
GAA P10253 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SOAT1 P35610 2/20 0.43
DEGS1 O15121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129147 0.98 HPGD (0.48) HPGDTRPV1ENPP2DGAT2LMNA
SCHEMBL13129142 0.94 HPGD (0.50) HPGDPOLBRAB9ACETP
SCHEMBL14864152 0.93 HPGD (0.51) HPGDTRPV1ENPP2DGAT2LMNA
SCHEMBL13129141 0.91 HPGD (0.53) HPGDTRPV1ENPP2DGAT2LMNA
SCHEMBL13129138 0.86 HPGD (0.57) HPGDLMNAPOLBSMN1; SMN2CETP
SCHEMBL14864149 0.86 HPGD (0.56) HPGDENPP2DGAT2LMNAPOLB
SCHEMBL13129137 0.84 HPGD (0.58) HPGDENPP2DGAT2LMNAPOLB
SCHEMBL14864153 0.81 SOAT1 (0.48) HPGDENPP2DGAT2LMNAPOLB
SCHEMBL13129155 0.80 SOAT1 (0.47) HPGDLMNAPOLBNPC1RAB9A
SCHEMBL10667145 0.79 HSP90AA1 (0.61) ENPP2DGAT2LMNAPOLBCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420721-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2013-04-16 US disclosed