SCHEMBL13130239

SCHEMBL13130239

Cc1nc(-c2cccc(/C(N)=N/O)c2)no1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.64
CHRNA7 P36544 1/20 0.43
TP53 P04637 4/20 0.42
MAPT P10636 3/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
POLB P06746 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
KIFC1 Q9BW19 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
PLK1 P53350 1/20 0.40
KDM1A O60341 1/20 0.40
DAO P14920 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL326777 0.82 L3MBTL1 (0.68) L3MBTL1CHRNA7TP53MAPTNPC1
SCHEMBL30454185 0.82 L3MBTL1 (0.68) L3MBTL1CHRNA7TP53MAPTNPC1
SCHEMBL13130238 0.79 L3MBTL1 (1.00) L3MBTL1CHRNA7TP53MAPTNPC1
SCHEMBL16579433 0.79 TP53 (0.51) L3MBTL1TP53MAPTNPC1RAB9A
SCHEMBL16572041 0.78 PPARA (0.50) L3MBTL1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL15233029 0.78 PPARA (0.50) L3MBTL1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL30497107 0.78 L3MBTL1 (0.70) L3MBTL1TP53MAPTNPC1RAB9A
SCHEMBL225165 0.78 L3MBTL1 (0.70) L3MBTL1TP53MAPTNPC1RAB9A
SCHEMBL1020649 0.77 L3MBTL1 (0.68) L3MBTL1CHRNA7TP53MAPTNPC1
SCHEMBL13167067 0.76 SIRT2 (0.51) L3MBTL1MAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9481658-B2 Optical film, retardation plate, elliptica polarizing plate, liquid crystal display device and compound FUJIFILM CORPORATION (JP) 2016-11-01 US disclosed
US-20150080582-A1 OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND FUJIFILM CORPORATION (JP) 2015-03-19 US disclosed
US-8524334-B2 Optical film, retardation plate, elliptica polarizing plate, liquid crystal display device and compound FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-20100239788-A1 OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080582-A1 OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND PYM1, CCND2, CCNB2 L3MBTL1 101/4885CHRNA7 3866/4885TP53 2976/4885
US-20100239788-A1 OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND PYM1, CCND2, CCNB2 L3MBTL1 87/4885CHRNA7 3879/4885TP53 2833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.