Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.73 |
| ▸ | TUBB | P07437 | 6/20 | 0.73 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.73 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.73 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.73 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.73 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.73 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.73 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.73 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.73 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.73 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.73 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.73 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.73 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.73 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134097 | 1.00 | TUBB4A (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL125576 | 0.94 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17620459 | 0.94 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15147365 | 0.94 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16216860 | 0.93 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13134096 | 0.93 | NPC1 (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13130784 | 0.93 | NPC1 (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL126981 | 0.93 | NPC1 (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12107358 | 0.92 | NPC1 (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8546175 | 0.92 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247669-A1 | POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE | CERULEAN PHARMA INC. | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247669-A1 | POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE | LPXN, POLI, BRCA1 | TUBB4A 194/4885TUBB 206/4885TUBA3C 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.