Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | CBS | P35520 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132717 | 0.97 | PTPN11 (0.61) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132548 | 0.89 | NPC1 (0.50) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132577 | 0.86 | NPC1 (0.56) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132564 | 0.86 | KDR (0.49) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132700 | 0.86 | NPC1 (0.50) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132556 | 0.86 | ALDH1A1 (0.54) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132510 | 0.85 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL13132578 | 0.85 | CA12 (0.47) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132560 | 0.85 | NPC1 (0.47) | PTPN11NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13132544 | 0.85 | NPC1 (0.52) | PTPN11NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | PTPN11 4492/4885NPC1 1210/4885RAB9A 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.