SCHEMBL1313286

SCHEMBL1313286

O=Cc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.54
ERN1 O75460 6/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPK1 P28482 2/20 0.38
AHR P35869 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTPN1 P18031 2/20 0.34
CYP3A4 P08684 2/20 0.33
TTR P02766 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3134002 0.94 TDP1 (0.59) TDP1ERN1ALDH1A1MEN1KMT2A
SCHEMBL26908511 0.91 TDP1 (0.56) TDP1ERN1ALDH1A1MAPK1AHR
SCHEMBL1953389 0.88 TDP1 (0.52) TDP1ERN1ALDH1A1MAPK1AHR
SCHEMBL29556939 0.88 TDP1 (0.52) TDP1ERN1ALDH1A1MAPK1AHR
SCHEMBL30207763 0.81 TDP1 (0.48) TDP1ERN1ALDH1A1MEN1KMT2A
SCHEMBL1808858 0.81 TDP1 (0.48) TDP1ERN1ALDH1A1MEN1KMT2A
SCHEMBL8672712 0.81 TDP1 (0.48) TDP1ERN1ALDH1A1MEN1KMT2A
SCHEMBL7892856 0.79 GAA (0.50) TDP1ERN1ALDH1A1MAPK1MEN1
SCHEMBL3377931 0.79 ERN1 (0.54) TDP1ERN1ALDH1A1MEN1KMT2A
SCHEMBL6187165 0.79 TDP1 (0.46) TDP1ERN1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178121-A Preparation method of 2,4, 5-trifluoro-benzaldehyde 浙江巍华新材料股份有限公司 2023-05-30 CN claimed
CN-111499506-A Green production process of 2, 4-dichloro-5-fluorobenzoyl chloride 浙江本立科技股份有限公司 2020-08-07 CN claimed
US-9234087-B2 Preparation for initiating radical reactions UNITED INITIATORS GMBH & CO. KG (DE) 2016-01-12 US claimed
EP-2288652-B1 PREPARATION FOR INITIATING RADICAL REACTIONS UNITED INITIATORS GMBH & CO KG (DE) 2012-09-19 EP claimed
EP-2130858-B1 Preparations to initiate radical reactions UNITED INITIATORS GMBH & CO KG (DE) 2012-07-25 EP claimed
US-20110272628-A1 Preparation For Initiating Radical Reactions UNITED INITIATORS GMBH (DE) 2011-11-10 US claimed
EP-2288652-A1 PREPARATION FOR INITIATING RADICAL REACTIONS United Initiators GmbH & Co. KG (DE) 2011-03-02 EP claimed
WO-2009146916-A1 PREPARATION FOR INITIATING RADICAL REACTIONS UNITED INITIATORS GMBH & CO. KG (DE) 2009-12-10 WO claimed
EP-2130858-A1 Preparations to initiate radical reactions Degussa Initiators GmbH & Co. KG (DE) 2009-12-09 EP claimed
CN-116178121-A Preparation method of 2,4, 5-trifluoro-benzaldehyde 浙江巍华新材料股份有限公司 2023-05-30 CN disclosed
CN-116178121-A Preparation method of 2,4, 5-trifluoro-benzaldehyde 浙江巍华新材料股份有限公司 2023-05-30 CN disclosed
CN-107820518-B Methods for selecting phosphatase selective inhibitors and non-selective phosphatase inhibitors 英国研究与创新署 2023-04-21 CN disclosed
US-11547747-B2 Treatment and detection of infection and disease associated with different fungal pathogens UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2023-01-10 US disclosed
US-20220401533-A1 TREATMENT AND PROTECTION AGAINST ASPERGILLUS INFECTION AND ASPERGILLOSIS DISEASE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2022-12-22 US disclosed
EP-0041675-A2 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
US-4205193-A CATALYST FROM ALUMINUM AND TITANIUM COMPOUND, ORGANOOXYGEN COMPOUND AND ORGANOSULFUR CONTAINING COMPOUND MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1980-05-27 US disclosed
US-4018926-A Alkyl 4-[o-(substituted methyleneamino)-phenyl]-3-thioallophanate miticides and fungicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-19 US disclosed
US-4011213-A FUNGICIDES, MITE OVICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-03-08 US disclosed
US-3984438-A INSECTICIDES AND FIRE RETARDANTS HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-10-05 US disclosed
US-3958007-A FUNGICIDES, MITE OVICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11547747-B2 Treatment and detection of infection and disease associated with different fungal pathogens KLK3, KLKB1, KLK5 TDP1 3201/4885ERN1 1053/4885ALDH1A1 4865/4885
US-20220401533-A1 TREATMENT AND PROTECTION AGAINST ASPERGILLUS INFECTION AND ASPERGILLOSIS DISEASE KLKB1, MASP2, ANTXR2 TDP1 3896/4885ERN1 1254/4885ALDH1A1 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.