Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114733 | 0.90 | CNR1 (0.51) | CNR1CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL5795340 | 0.89 | CNR1 (0.52) | CNR1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL3561075 | 0.89 | CNR1 (0.57) | CNR1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL5795343 | 0.87 | CNR1 (0.47) | CNR1CYP3A4CYP2C9CYP2C19MALT1 | |
| SCHEMBL13114664 | 0.78 | CNR1 (0.54) | CNR1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL13114724 | 0.76 | CNR1 (0.54) | CNR1CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL13114655 | 0.75 | CNR1 (0.51) | CNR1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL4806813 | 0.74 | CNR1 (0.73) | CNR1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL5796174 | 0.73 | CNR1 (0.54) | CNR1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL3550428 | 0.73 | CNR1 (0.59) | CNR1CYP3A4CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816357-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-19 | — | — | US | disclosed |