Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.41 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560391 | 0.93 | TGM2 (0.49) | NPY4RTGM2AVPR2FPR2TLR7 | |
| SCHEMBL3554432 | 0.92 | TGM2 (0.50) | NPY4RTGM2AVPR2FPR2CHRM1 | |
| SCHEMBL13135018 | 0.83 | TGM2 (0.54) | NPY4RTGM2AVPR2FPR2CHRM1 | |
| SCHEMBL13114579 | 0.83 | TGM2 (0.58) | NPY4RTGM2AVPR2FPR2CHRM1 | |
| SCHEMBL3559860 | 0.82 | NPY4R (0.47) | NPY4RTGM2AVPR2TLR7 | |
| SCHEMBL13134614 | 0.81 | TGM2 (0.49) | NPY4RTGM2AVPR2FPR2CHRM1 | |
| SCHEMBL3556799 | 0.81 | TGM2 (0.50) | NPY4RTGM2AVPR2FPR2TLR7 | |
| SCHEMBL3555484 | 0.81 | TGM2 (0.50) | NPY4RTGM2AVPR2FPR2CHRM1 | |
| SCHEMBL13135699 | 0.80 | TGM2 (0.48) | NPY4RTGM2AVPR2FPR2CHRM1 | |
| SCHEMBL12870952 | 0.79 | TGM2 (0.60) | NPY4RTGM2AVPR2FPR2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820833-B2 | Dithio compounds | MARQUETTE UNIVERSITY (US) | 2010-10-26 | — | — | US | disclosed |