Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390791 | 0.90 | SYK (0.44) | SYK | |
| SCHEMBL13136232 | 0.87 | SYK (0.55) | SYK | |
| SCHEMBL13136265 | 0.86 | SYK (0.57) | SYK | |
| SCHEMBL2862308 | 0.85 | SYK (0.56) | SYK | |
| SCHEMBL13136656 | 0.82 | SYK (0.51) | SYK | |
| SCHEMBL13136225 | 0.81 | SYK (0.52) | SYK | |
| SCHEMBL13136662 | 0.80 | SYK (0.50) | SYK | |
| SCHEMBL13136201 | 0.80 | SYK (0.56) | SYK | |
| SCHEMBL2859181 | 0.79 | SYK (0.54) | SYK | |
| SCHEMBL2859189 | 0.79 | SYK (0.54) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803801-B2 | Aminopyridine compounds having Syk inhibitory activity | JAPAN TOBACCO, INC. (JP) | 2010-09-28 | — | — | US | disclosed |
| US-7803801-B2 | Aminopyridine compounds having Syk inhibitory activity | JAPAN TOBACCO, INC. (JP) | 2010-09-28 | — | — | US | disclosed |