Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675745 | 0.84 | CNR2 (0.68) | CNR2PIK3CAPIK3CDERN1PIK3CG | |
| SCHEMBL16773016 | 0.82 | CNR2 (0.69) | CNR2 | |
| SCHEMBL1311387 | 0.81 | PIK3CA (0.69) | PIK3CAPIK3CDPIK3CBPIK3CGHSD17B1 | |
| SCHEMBL1443001 | 0.81 | PIK3CA (0.58) | CNR2PIK3CAPIK3CDFYNPIK3CB | |
| SCHEMBL31590101 | 0.80 | FYN (0.53) | CNR2PIK3CAFYNAOC3HSD17B1 | |
| SCHEMBL3244371 | 0.80 | CNR2 (0.67) | CNR2ERN1AOC3 | |
| SCHEMBL28146287 | 0.78 | CNR2 (0.64) | CNR2PIK3CAERN1PIK3CBAOC3 | |
| SCHEMBL16053927 | 0.77 | CNR2 (0.66) | CNR2ERN1 | |
| SCHEMBL4856203 | 0.77 | ALDH1A1 (0.58) | CNR2 | |
| SCHEMBL31104721 | 0.77 | ALDH1A1 (0.58) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799778-B1 | 5-substituted 2-aminopyridine analogs for treating allergic and inflammatory diseases | ALCON, INC. (CH) | 2010-09-21 | — | — | US | disclosed |
| US-7799778-B1 | 5-substituted 2-aminopyridine analogs for treating allergic and inflammatory diseases | ALCON, INC. (CH) | 2010-09-21 | — | — | US | disclosed |