Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468455 | 0.81 | AKR1B1 (0.55) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| Methyl Alcohol SCHEMBL28299530 | 0.80 | AKR1B1 (0.70) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL30359 | 0.79 | AKR1B1 (0.76) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL29410826 | 0.79 | AKR1B1 (0.76) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| Hydrochloric Acid SCHEMBL11484601 | 0.79 | AKR1B1 (0.53) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL4032382 | 0.79 | AKR1B1 (0.57) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL3053777 | 0.78 | TAAR1 (0.61) | TAAR1ATMTDP1MTNR1AMTNR1B | |
| SCHEMBL11526125 | 0.78 | FOLH1 (0.59) | TAAR1ATMALDH1A1HTT | |
| SCHEMBL28842838 | 0.77 | AKR1B1 (0.73) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| Hydrochloric Acid SCHEMBL6767821 | 0.77 | AKR1B1 (0.73) | AKR1B1TDP1PTGS2BCAT2CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222326-A1 | New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders | UCB PHARMA, S.A. (BE) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222326-A1 | New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders | CNR2, CNR1, SLC18A2 | AKR1B1 1913/4885TAAR1 160/4885ATM 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.