⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705554 | 0.72 | — | — | |
| Dibromochloromethane SCHEMBL76438 | 0.72 | — | — | |
| Bromodichloromethane SCHEMBL75683 | 0.72 | — | — | |
| SCHEMBL95260 | 0.72 | — | — | |
| SCHEMBL23396 | 0.72 | — | — | |
| SCHEMBL4810225 | 0.71 | — | — | |
| SCHEMBL20448722 | 0.69 | — | — | |
| SCHEMBL11274911 | 0.67 | — | — | |
| Water SCHEMBL3326761 | 0.67 | LMNA (0.38) | — | |
| Bromodichloromethane SCHEMBL20771573 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273726-B2 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | BRANDEIS UNIVERSITY (US) | 2012-09-25 | — | — | US | disclosed |
| US-20110275703-A1 | SUBSTITUTED SPIROKETAL DERIVATIVES AND USE THEREOF AS THERAPEUTIC DRUG FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20100184724-A1 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | GRENPHARMA LLC (US) | 2010-07-22 | — | — | US | disclosed |
| US-7595308-B2 | Treatment and/or prevention of Alzheimer's disease, other neurodegenerative diseases, and/or diseases characterized by the presence of certain metal ions, by using organosilicon compounds such as dichlorodiethylsilane | GRENPHARMA LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090203644-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | GRENPHARMA LLC (US) | 2009-08-13 | — | — | US | disclosed |
| EP-2048153-A1 | SUBSTITUTED SPIROKETAL DERIVATIVE AND USE THEREOF AS DRUG FOR TREATING DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1583765-A4 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | GRENPHARMA LLC (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1812013-A1 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF THE METAL IONS | Grenpharma LLC (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006047477-A1 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF THE METAL IONS | GRENPHARAMA LLC (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060040897-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | GRENPHARMA, LLC | 2006-02-23 | — | — | US | disclosed |
| EP-1583765-A2 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | Grenpharma LLC (US) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004045552-A2 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | GRENPHARMA LLC (US) | 2004-06-03 | — | — | WO | disclosed |
| US-5466710-A | Heterobicycloalkanes as pesticidal compounds | ROUSSEL UCLAF (FR) | 1995-11-14 | — | — | US | disclosed |
| US-5039693-A | Pyrazole amides and insecticide and miticide containing them as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0365925-A1 | Pyrazole amides and insecticide and miticide containing them as active ingredient | Mitsubishi Chemical Corporation (JP) | 1990-05-02 | — | — | EP | disclosed |