Trolamine

Trolamine

SCHEMBL1314119

CCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCCCC(=O)O)C(=O)O.OCCN(CCO)CCO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 2/20 0.54
▸ FFAR1 O14842 2/20 0.54
▸ GPR84 Q9NQS5 7/20 0.52
▸ PPARG P37231 7/20 0.52
▸ PPARD Q03181 7/20 0.52
▸ PPARA Q07869 7/20 0.52
▸ HDAC11 Q96DB2 5/20 0.52
▸ TSHR P16473 4/20 0.52
▸ PTPN1 P18031 3/20 0.52
▸ ALDH1A1 P00352 2/20 0.52
▸ TLR2 O60603 2/20 0.52
▸ TDP1 Q9NUW8 2/20 0.52
▸ FABP4 P15090 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ SLC22A6 Q4U2R8 1/20 0.52
▸ SLC22A8 Q8TCC7 1/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ ESR1 P03372 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ PDE4A P27815 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19032582 0.88 GRIK1 (0.49) FFAR1GPR84PPARDTDP1MAPT
SCHEMBL25423187 0.88 GRIK1 (0.49) FFAR1GPR84PPARDTDP1MAPT
Stearic Acid SCHEMBL27442953 0.87 FFAR4 (0.61) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL6156790 0.87 FFAR4 (0.69) FFAR4FFAR1GPR84PPARGPPARD
Octanoic Acid SCHEMBL20394217 0.87 FFAR4 (0.69) FFAR4FFAR1GPR84PPARGPPARD
Decanoic Acid SCHEMBL8937980 0.87 FFAR4 (0.69) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL5820782 0.87 FFAR4 (0.69) FFAR4FFAR1GPR84PPARGPPARD
Behenic Acid SCHEMBL20658937 0.87 FFAR4 (0.69) FFAR4FFAR1GPR84PPARGPPARD
Palmitic Acid SCHEMBL20876307 0.87 FFAR4 (0.69) FFAR4FFAR1GPR84PPARGPPARD
Myristic Acid SCHEMBL25309729 0.87 FFAR4 (0.69) FFAR4FFAR1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2088895-B1 SINGLE-USE PERSONAL CARE PRODUCTS AND KITS COMPRISING SAME PROCTER & GAMBLE (US) 2016-07-20 — — EP disclosed
EP-1879550-B1 SHAVE GEL COMPOSITION CONTAINING GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER GILLETTE CO (US) 2015-07-01 — — EP disclosed
EP-2838499-A2 PERSONAL CARE COMPOSITION COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS The Gillette Company (US) 2015-02-25 — — EP disclosed
US-20140287007-A1 AEROSOL SHAVE COMPOSITION COMPRISING A HYDROPHOBICAL AGENT FORMING AT LEAST ONE MICRODROPLET GILLETTE CO (US) 2014-09-25 — — US disclosed
EP-2231104-B1 PERSONAL CARE COMPOSITIONS CONTAINING SKIN CONDITIONING AGENTS PROCTER & GAMBLE (US) 2013-12-18 — — EP disclosed
WO-2013158964-A2 PERSONAL CARE COMPOSITION COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS THE GILLETTE COMPANY (US) 2013-10-24 — — WO disclosed
US-20130280174-A1 PERSONAL CARE COMPOSITION COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS THE GILLETTE COMPANY (US) 2013-10-24 — — US disclosed
EP-2566434-A2 AN AEROSOL SHAVE COMPOSITION COMPRISING A HYDROPHOBICAL AGENT FORMING AT LEAST ONE MICRODROPLET The Gillette Company (US) 2013-03-13 — — EP disclosed
EP-2566435-A2 METHOD OF MAKING AN AEROSOL SHAVE COMPOSITION COMPRISING A HYDROPHOBICAL AGENT FORMING AT LEAST ONE MICRODROPLET The Gillette Company (US) 2013-03-13 — — EP disclosed
WO-2013025891-A1 AN AEROSOL SHAVE COMPOSITION COMPRISING A HYDROPHOBICAL AGENT FORMING AT LEAST ONE MICRODROPLET AND AN ANTI-IRRITATION AGENT THE GILLETTE COMPANY (US) 2013-02-21 — — WO disclosed
US-20080206165-A1 Single-use personal care products and kits comprising same PROCTER & GAMBLE COMPANY, THE 2008-08-28 — — US disclosed
WO-2008072189-A1 SINGLE-USE PERSONAL CARE PRODUCTS AND KITS COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2008-06-19 — — WO disclosed
EP-1879550-A1 SHAVE GEL COMPOSITION CONTAINING GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER THE GILLETTE COMPANY (US) 2008-01-23 — — EP disclosed
EP-1879540-A1 SHAVE COMPOSITION CONTAINING THREE TYPES OF LUBRICANTS THE GILLETTE COMPANY (US) 2008-01-23 — — EP disclosed
WO-2007112266-A1 LINERS FOR AEROSOL PACKAGES AND ARTICLES COMPRISING SAME THE GILLETTE COMPANY (US) 2007-10-04 — — WO disclosed
US-20070221685-A1 Liners for aerosol packages and articles comprising same PROCTER & GAMBLE COMPANY, THE 2007-09-27 — — US disclosed
WO-2006124220-A1 SHAVE GEL COMPOSITION CONTAINING GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER THE GILLETTE COMPANY (US) 2006-11-23 — — WO disclosed
WO-2006124219-A1 SHAVE COMPOSITION CONTAINING THREE TYPES OF LUBRICANTS THE GILLETTE COMPANY (US) 2006-11-23 — — WO disclosed
US-20060257349-A1 about 60% to 93% water, about 2% to 25% water dispersible surface active agent( anionic, nonionic or amphoteri surfactants) 1% to 6% volatile post-foaming agent ( isopnentane), about 0.0005% to 1% glyceryl acrylate/acrylic acid copolymer, and a gelling aid ( polyethylene oxide) and a package; moistening THE GILLETTE COMPANY 2006-11-16 — — US disclosed
US-20060257350-A1 Shave composition containing three types of lubricants THE GILLETTE COMPANY 2006-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130280174-A1 PERSONAL CARE COMPOSITION COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS CUTA, PARG, PARN FFAR4 189/4885FFAR1 30/4885GPR84 810/4885
US-20140287007-A1 AEROSOL SHAVE COMPOSITION COMPRISING A HYDROPHOBICAL AGENT FORMING AT LEAST ONE MICRODROPLET HTT, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MFAP1 FFAR4 2685/4885FFAR1 2514/4885GPR84 3028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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