Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | MERTK | Q12866 | 1/20 | 0.46 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145329 | 0.81 | LRRK2 (0.44) | CNR2 | |
| SCHEMBL541605 | 0.79 | CNR2 (0.62) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL541606 | 0.79 | CNR2 (0.62) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL541562 | 0.77 | CNR2 (0.64) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL13503371 | 0.77 | CNR2 (0.79) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL13069958 | 0.77 | CNR2 (0.80) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL6061291 | 0.77 | CNR2 (0.73) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL14307828 | 0.76 | CNR2 (0.64) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4419263 | 0.76 | CNR2 (0.82) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL13069959 | 0.76 | CNR2 (1.00) | CNR2CYP1A2CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010113834-A1 | PYRIMIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-07 | — | — | WO | disclosed |