SCHEMBL13144302

SCHEMBL13144302

COC(=O)C(C)(C)CSc1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
ALDH1A1 P00352 5/20 0.40
LMNA P02545 3/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
RECQL P46063 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 3/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2116085 0.74 CYP1A2 (0.54) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL19403441 0.72 HSD17B10 (0.42) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28023328 0.72 CYP2C19 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28059815 0.70 IFNAR1 (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8122615 0.70 ALDH1A1 (0.44) ALDH1A1LMNAHPGDSMN1; SMN2KDM4E
SCHEMBL24821171 0.69 PLCG1 (0.47) ALDH1A1HPGDMEN1KMT2AHSD17B10
SCHEMBL3077714 0.68 MEN1 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL10412004 0.68 ALDH1A1 (0.44) ALDH1A1HPGDMEN1KMT2AHSD17B10
SCHEMBL8563130 0.68 ALDH1A1 (0.44) ALDH1A1HPGDMEN1KMT2AHSD17B10
SCHEMBL28702281 0.68 ALDH1A1 (0.63) ALDH1A1LMNAHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921018-B2 Polymer compound and production method thereof, pigment dispersing agent, pigment dispersion composition, photocurable composition, and color filter and production method thereof FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-8808947-B2 Polymer compound and production method thereof, pigment dispersing agent, pigment dispersion composition, photocurable composition, and color filter and production method thereof FUJIFILM CORPORATION (JP) 2014-08-19 US disclosed
US-20140175348-A1 POLYMER COMPOUND AND PRODUCTION METHOD THEREOF, PIGMENT DISPERSING AGENT, PIGMENT DISPERSION COMPOSITION, PHOTOCURABLE COMPOSITION, AND COLOR FILTER AND PRODUCTION METHOD THEREOF FUJIFILM CORPORATION (JP) 2014-06-26 US disclosed
US-20100233595-A1 POLYMER COMPOUND AND PRODUCTION METHOD THEREOF, PIGMENT DISPERSING AGENT, PIGMENT DISPERSION COMPOSITION, PHOTOCURABLE COMPOSITION, AND COLOR FILTER AND PRODUCTION METHOD THEREOF FUJIFILM CORPORATION (JP) 2010-09-16 US disclosed