SCHEMBL13147141

SCHEMBL13147141

c1ccc(N(c2ccccc2)c2ccc(-c3c4ccccc4c(-c4ccc5c(ccc6ccccc65)c4)c4ccccc34)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP1B1 Q16678 2/20 0.42
HIF1A Q16665 2/20 0.42
HPRT1 P00492 3/20 0.41
ALOX5 P09917 1/20 0.40
SOS1 Q07889 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
CYP1A2 P05177 5/20 0.38
CYP2D6 P10635 3/20 0.38
CYP2C9 P11712 3/20 0.38
CYP2C19 P33261 3/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B1 P14061 1/20 0.38
CYP2B6 P20813 1/20 0.38
HSD17B2 P37059 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24372512 0.95 HPRT1 (0.44) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL12014702 0.94 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL13015753 0.92 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL13304038 0.91 CYP1B1 (0.38) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL12703059 0.90 ESR1 (0.41) ALDH1A1HSD17B10CYP1B1ALOX5TDP1
SCHEMBL10063914 0.90 ESR1 (0.41) ALDH1A1HSD17B10CYP1B1ALOX5TDP1
SCHEMBL13303968 0.90 CYP1B1 (0.37) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL12014704 0.90 CYP1B1 (0.37) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL12014703 0.89 ESR1 (0.39) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL12571735 0.89 ESR1 (0.38) ALDH1A1CYP1B1ALOX5TDP1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010114256-A2 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOW ADVANCED DISPLAY MATERIALS,LTD. (KR) 2010-10-07 WO disclosed