Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 19/20 | 0.69 |
| ▸ | CCR5 | P51681 | 1/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL313017 | 0.99 | CCR2 (0.68) | CCR2CCR5PTGDR2 | |
| SCHEMBL13148354 | 0.91 | CCR2 (0.60) | CCR2CCR5PTGDR2 | |
| Iodide SCHEMBL17555127 | 0.90 | CCR2 (0.59) | CCR2CCR5PTGDR2 | |
| Hydrochloric Acid SCHEMBL2907331 | 0.90 | CCR2 (0.59) | CCR2CCR5PTGDR2 | |
| Iodide SCHEMBL17555075 | 0.86 | CCR2 (0.67) | CCR2CCR5 | |
| Hydrochloric Acid SCHEMBL313312 | 0.86 | CCR2 (0.67) | CCR2CCR5 | |
| SCHEMBL13148114 | 0.82 | CCR2 (1.00) | CCR2CCR5 | |
| SCHEMBL13148183 | 0.81 | CCR2 (1.00) | CCR2CCR5 | |
| Hydrochloric Acid SCHEMBL2901075 | 0.81 | CCR2 (0.98) | CCR2CCR5 | |
| SCHEMBL13148171 | 0.81 | CCR2 (0.83) | CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799824-B2 | Quaternary salt CCR2 antagonists | ORAPHARMA, INC. (US) | 2010-09-21 | — | — | US | disclosed |