Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460813 | 1.00 | KCNH2 (0.64) | KCNH2CCR2 | |
| SCHEMBL13110004 | 0.93 | CCR2 (0.54) | KCNH2CCR2 | |
| SCHEMBL13110074 | 0.93 | CCR2 (0.54) | KCNH2CCR2 | |
| SCHEMBL3462169 | 0.85 | KCNH2 (0.64) | KCNH2CCR2 | |
| SCHEMBL13150943 | 0.85 | KCNH2 (0.64) | KCNH2CCR2 | |
| SCHEMBL13110015 | 0.82 | CCR2 (0.70) | KCNH2CCR2 | |
| SCHEMBL3461497 | 0.82 | CCR2 (0.70) | KCNH2CCR2 | |
| SCHEMBL13148646 | 0.82 | KCNH2 (0.67) | KCNH2CCR2 | |
| SCHEMBL3460826 | 0.82 | KCNH2 (0.67) | KCNH2CCR2 | |
| SCHEMBL13110014 | 0.82 | CCR2 (0.66) | KCNH2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419418-B1 | 4-AZETIDINYL-1-HETEROATOM LINKED-CYCLOHEXANE ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-15 | — | — | EP | disclosed |
| WO-2010121036-A1 | 4-AZETIDINYL-1-HETEROATOM LINKED-CYCLOHEXANE ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-21 | — | — | WO | disclosed |