Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149704 | 1.00 | CYP19A1 (0.52) | CYP19A1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28565817 | 0.86 | LMNA (0.57) | CYP19A1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28562858 | 0.86 | LMNA (0.57) | CYP19A1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16361071 | 0.86 | KCNN4 (0.46) | CYP19A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL7024646 | 0.83 | — | — | |
| SCHEMBL35226 | 0.83 | — | — | |
| SCHEMBL5776485 | 0.83 | — | — | |
| SCHEMBL4476738 | 0.82 | CYP19A1 (0.50) | CYP19A1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7940880 | 0.80 | KMT2A (0.50) | CYP19A1TSHRSMN1; SMN2NPC1RAB9A | |
| Fluoride SCHEMBL21986315 | 0.80 | LMNA (0.57) | CYP19A1TSHRSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | PAH, TSNAX, ZFX | CYP19A1 157/4885TSHR 2120/4885SMN1; SMN2 2312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.