Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539120 | 0.84 | CYP11B1 (0.65) | CYP11B1CYP11B2PGRNPC1CYP3A4 | |
| SCHEMBL12232435 | 0.81 | CYP11B1 (0.55) | CYP11B1CYP11B2MEN1KMT2ACRBN | |
| SCHEMBL2850811 | 0.81 | MEN1 (0.68) | AHRMEN1KMT2ACMA1ATM | |
| SCHEMBL1119436 | 0.80 | KMT2A (0.68) | CYP11B1CYP11B2AHRMEN1KMT2A | |
| SCHEMBL31083654 | 0.80 | CYP11B1 (0.53) | CYP11B1CYP11B2MEN1KMT2ACRBN | |
| SCHEMBL3588988 | 0.80 | CYP11B1 (0.53) | CYP11B1CYP11B2MEN1KMT2ACRBN | |
| SCHEMBL13150727 | 0.80 | CYP11B1 (0.53) | CYP11B1CYP11B2MEN1KMT2ACRBN | |
| SCHEMBL3588987 | 0.80 | CYP11B1 (0.53) | CYP11B1CYP11B2MEN1KMT2ACRBN | |
| SCHEMBL19046942 | 0.78 | CYP11B1 (0.51) | CYP11B1CYP11B2MEN1KMT2AATM | |
| SCHEMBL30379985 | 0.76 | CYP11B1 (0.71) | CYP11B1CYP11B2MEN1KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116270-A1 | EP2/4 AGONISTS | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |