Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CCR1 | P32246 | 3/20 | 0.61 |
| ▸ | CCR5 | P51681 | 3/20 | 0.61 |
| ▸ | CCR8 | P51685 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL1456977 | 0.81 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| Dipyridyl SCHEMBL27635154 | 0.81 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL379708 | 0.81 | KDM4E (0.32) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30211369 | 0.79 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL1456153 | 0.79 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL1456985 | 0.79 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL1181563 | 0.78 | KDM4E (0.88) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| Charcoal, Activated SCHEMBL30558882 | 0.78 | KDM4E (0.31) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| Dipyridyl SCHEMBL3711450 | 0.78 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| Dipyridyl SCHEMBL29907716 | 0.78 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12466812-B2 | Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2025-11-11 | — | — | US | claimed |
| US-20240349602-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-10-17 | — | — | US | claimed |
| CN-117185927-B | Method for synthesizing methyl isononanoate from diisobutylene | 广东仁康达材料科技有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-117777167-A | 2-TPT-based photochromic Cd complex and preparation method thereof | 福建工程学院 | 2024-03-29 | — | — | CN | claimed |
| CN-117497784-A | Dy-based doped nitrogen-carbon-oxygen reduction catalyst and preparation method and application thereof | 广西大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117364122-A | Preparation method and application of organic hybrid manganese sulfide electrocatalytic oxygen evolution material | 重庆师范大学 | 2024-01-09 | — | — | CN | claimed |
| CN-117185927-A | Method for synthesizing methyl isononanoate from diisobutylene | 广东仁康达材料科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116903676-A | Structure-adjustable triazinyl metal organic cage and preparation method and application thereof | 西安交通大学 | 2023-10-20 | — | — | CN | claimed |
| US-20230027716-A1 | NOVEL PYRIDINYLTRIAZINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING CANCER COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-01-26 | — | — | US | claimed |
| CN-114335566-A | Ni/Co-N doped porous carbon-oxygen reduction catalyst and preparation method thereof | 河南工业大学 | 2022-04-12 | — | — | CN | claimed |
| CN-101994124-A | Heterocyclic carbon steel pickling corrosion inhibitor and application thereof | INST OCEANOLOGY CHINESE ACAD | 2011-03-30 | — | — | CN | claimed |
| CN-100537562-C | Pyridyl-triazine derivatives as microbicidal active substances | CIBA SC HOLDING AG (CH) | 2009-09-09 | — | — | CN | claimed |
| JP-2006505514-A | — | — | 2006-02-16 | — | — | JP | claimed |
| US-20050267109-A1 | Pyridyl-triazine derivatives as microbiocidal active substances | CIBA SPECIALTY CHEMICALS CORP. | 2005-12-01 | — | — | US | claimed |
| CN-1671689-A | Pyridyl-triazine derivatives as microbicidal active substances | CIBA SC HOLDING AG (CH) | 2005-09-21 | — | — | CN | claimed |
| EP-1525196-A1 | PYRIDYL-TRIAZINE DERIVATIVES AS MICROBICIDAL ACTIVE SUBSTANCES | Ciba SC Holding AG (CH) | 2005-04-27 | — | — | EP | claimed |
| WO-2004013124-A1 | PYRIDYL-TRIAZINE DERIVATIVES AS MICROBICIDAL ACTIVE SUBSTANCES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-02-12 | — | — | WO | claimed |
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | claimed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | claimed |
| US-4418221-A | SOLVENT EXTRACTION WITH A NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS | KOEI CHEMICAL CO., LTD. (JP) | 1983-11-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12466812-B2 | Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same | FGFR3, FGFR1, FGFR4 | KDM4E 953/4885NPC1 4489/4885RAB9A 2734/4885 |
| US-20050267109-A1 | Pyridyl-triazine derivatives as microbiocidal active substances | C3AR1, C1S, C5 | KDM4E 4134/4885NPC1 2326/4885RAB9A 3467/4885 |
| US-20230027716-A1 | NOVEL PYRIDINYLTRIAZINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING CANCER COMPRISING SAME | FGFR3, FGFR1, FGFR4 | KDM4E 1032/4885NPC1 4592/4885RAB9A 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.