SCHEMBL379708

SCHEMBL379708

c1cc(-c2ccnnn2)nnn1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Charcoal, Activated SCHEMBL30558882 0.97 KDM4E (0.31) KDM4ENPC1ALDH1A1LMNATP53
SCHEMBL14335771 0.87 GABRA1 (0.31)
SCHEMBL31229097 0.84 KDM4E (0.44) KDM4ENPC1ALDH1A1LMNATP53
SCHEMBL31413695 0.83 KDM4E (0.37) KDM4E
SCHEMBL31030231 0.83 CCR1 (0.32) KDM4ELMNATP53ALOX15HTT
SCHEMBL16731967 0.81 ALDH1A1 (0.32) KDM4ENPC1ALDH1A1LMNATP53
SCHEMBL2086503 0.79
SCHEMBL5552035 0.79 NISCH (0.36) NPC1ALDH1A1PKMRAB9A
SCHEMBL17104879 0.79
SCHEMBL1905674 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11926079-B2 Foam fabric Taikone Technologies Inc. (CN) 2024-03-12 US claimed
CN-113234095-B Bitriazine group-containing compound and application thereof as three-dimensional electron acceptor material 武汉工程大学 2022-09-27 CN claimed
CN-119751904-A Preparation method of bio-based epoxy resin/carbon fiber composite material 中南民族大学 2025-04-04 CN disclosed
CN-119118995-A Phenyl diphenyl pyrimidine compound and organic electroluminescent device thereof 昱镭光电科技股份有限公司 2024-12-13 CN disclosed
US-11926079-B2 Foam fabric Taikone Technologies Inc. (CN) 2024-03-12 US disclosed
US-11926079-B2 Foam fabric Taikone Technologies Inc. (CN) 2024-03-12 US disclosed
CN-114585620-B Oxadiazole compounds or salts thereof, agrohorticultural fungicides containing the same, and methods of use thereof 日本农药株式会社 2024-02-23 CN disclosed
US-20240010805-A1 BMI RESIN FORMULATION FOR CARBON FIBER REINFORCED COMPOSITE MATERIAL, METHOD FOR MAKING IT AND BMI PREPREG TORAY COMPOSITE MATERIALS AMERICA, INC. (US) 2024-01-11 US disclosed
EP-4255968-A1 BMI RESIN FORMULATION FOR CARBON FIBER REINFORCED COMPOSITE MATERIAL, METHOD FOR MAKING IT AND BMI PREPREG Toray Composite Materials America, Inc. (US) 2023-10-11 EP disclosed
EP-4039774-B1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-09-20 EP disclosed
EP-3279961-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-07-19 EP disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
EP-1363705-A1 COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2003-11-26 EP disclosed
US-20030207910-A1 Treatment of HIV and AIDS VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2003-11-06 US disclosed
WO-2003068221-A1 INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC PYRROLIDINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2003-08-21 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-20030069266-A1 Aids therapy VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2003-04-10 US disclosed
WO-2002062423-A1 COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069266-A1 Aids therapy ENTPD5, CCR5, ITPA KDM4E 1105/4885NPC1 629/4885ALDH1A1 801/4885
US-20030207910-A1 Treatment of HIV and AIDS CD4, CCR5, IDO1 KDM4E 1025/4885NPC1 713/4885ALDH1A1 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.