Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 6/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526899 | 0.76 | NOTUM (1.00) | NOTUMHTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL31504075 | 0.76 | NOTUM (1.00) | NOTUMHTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL31504074 | 0.76 | NOTUM (1.00) | NOTUMHTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL24651170 | 0.73 | NOTUM (0.66) | NOTUMHTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL8526283 | 0.73 | NOTUM (0.66) | NOTUMHTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL1575886 | 0.73 | NOTUM (0.66) | NOTUMHTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL326944 | 0.73 | NOTUM (0.41) | NOTUMHTR2AHTR2CHTR2BPARP1 | |
| Hydrochloric Acid SCHEMBL15311720 | 0.72 | NOTUM (0.40) | NOTUMHTR2AHTR2CHTR2BPARP1 | |
| SCHEMBL5754293 | 0.70 | PNMT (0.55) | NOTUMARPARP1 | |
| SCHEMBL10733139 | 0.70 | AR (0.50) | HTR2AHTR2CHTR2BARTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118287-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2010-10-14 | — | — | WO | disclosed |