Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112550 | 1.00 | USP30 (0.56) | USP30RXFP1AHRANO1F10 | |
| SCHEMBL13151484 | 0.85 | RXFP1 (0.52) | USP30RXFP1AHRMEN1KMT2A | |
| SCHEMBL47199 | 0.85 | RXFP1 (0.52) | USP30RXFP1AHRMEN1KMT2A | |
| SCHEMBL29779214 | 0.72 | USP30 (1.00) | USP30 | |
| SCHEMBL18124076 | 0.72 | USP30 (1.00) | USP30 | |
| SCHEMBL23585226 | 0.72 | USP30 (1.00) | USP30 | |
| SCHEMBL19332054 | 0.72 | USP30 (0.55) | USP30RXFP1MAPK8CNR1CNR2 | |
| SCHEMBL15077715 | 0.71 | JAK2 (0.47) | JAK2JAK1 | |
| SCHEMBL16192279 | 0.71 | JAK2 (0.47) | JAK2JAK1 | |
| SCHEMBL19992743 | 0.68 | GPR119 (0.50) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010119984-A1 | 3-ARYL OR HETEROARYL-SUBSTITUTED INDOLE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-10-21 | — | — | WO | disclosed |