SCHEMBL131541

SCHEMBL131541

Cc1cscc1C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL444735 0.80
SCHEMBL3078486 0.74
SCHEMBL16288977 0.74
SCHEMBL16289657 0.70
SCHEMBL129408 0.69
SCHEMBL4734655 0.69 KDM5A (0.33)
SCHEMBL29955746 0.69 ENPP2 (0.32)
SCHEMBL5957187 0.69
SCHEMBL10192282 0.69
SCHEMBL10193073 0.69 AR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
US-7368470-B2 Substituted 3-pyrrolidine-indole derivatives GRUENENTHAL GMBH (DE) 2008-05-06 US claimed
JP-2007501828-A 2007-02-01 JP claimed
EP-1654253-A1 SUBSTITUTED 3-PYRROLIDIN-INDOLE DERIVATIVES Grünenthal GmbH (DE) 2006-05-10 EP claimed
US-20050096376-A1 Substituted 3-pyrrolidine-indole derivatives GRUENENTHAL GMBH (DE) 2005-05-05 US claimed
WO-2005019208-A1 SUBSTITUTED 3-PYRROLIDIN-INDOLE DERIVATIVES Grünenthal GmbH (DE) 2005-03-03 WO claimed
US-20250295652-A1 Inhibitors of Molluscum Contagiosum Infection and Methods Using the Same UNIV PENNSYLVANIA (US) 2025-09-25 US disclosed
CN-118561809-A Functional lithium salt additive, selective ion conductor coating layer, electrolyte and lithium ion battery 江苏蓝固新能源科技有限公司 2024-08-30 CN disclosed
WO-2024137607-A1 THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2024-06-27 WO disclosed
CN-112538078-B Polycyclic compound for inhibiting DHX33 helicase 成都开悦生命科技有限公司 2024-03-19 CN disclosed
EP-4273147-A1 SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-11-08 EP disclosed
EP-3746451-B1 BENZYL-, (PYRIDIN-3-YL)METHYL- OR (PYRIDIN-4-YL)METHYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2023-07-12 EP disclosed
US-20230192613-A1 Charged Ion Channel Blockers and Methods for Use NOCION THERAPEUTICS INC (US) 2023-06-22 US disclosed
US-5731455-A ALKYL 2-ALKYLACYLACRYLATE CHEMICAL INTERMEDIATE; ANTICHOLESTEROL AGENTS SHIONOGI & CO., LTD. (JP) 1998-03-24 US disclosed
EP-0597107-B1 LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG SHIONOGI & CO (JP) 1996-07-03 EP disclosed
US-5502216-A ANTICHOLESTEROL SHIONOGI & CO., LTD. (JP) 1996-03-26 US disclosed
EP-0701991-A1 Process for the preparation of lignin analogues and starting materials therefor SHIONOGI & CO., LTD. (JP) 1996-03-20 EP disclosed
US-5449814-A Dehydration; Michael condensation SHIONOGI & CO., LTD. (JP) 1995-09-12 US disclosed
US-5420333-A Hydroxy ketone compounds SHIONOGI & CO., LTD. (JP) 1995-05-30 US disclosed
EP-0597107-A1 LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG SHIONOGI & CO., LTD. (JP) 1994-05-18 EP disclosed