⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172585 | 1.00 | — | — | |
| SCHEMBL24638638 | 0.85 | GAA (0.41) | — | |
| SCHEMBL24304905 | 0.85 | SIGMAR1 (0.36) | — | |
| SCHEMBL1997758 | 0.82 | — | — | |
| SCHEMBL25118617 | 0.82 | GAA (0.34) | — | |
| SCHEMBL10985073 | 0.80 | SIGMAR1 (0.48) | — | |
| SCHEMBL672953 | 0.80 | — | — | |
| SCHEMBL8529497 | 0.80 | GAA (0.33) | — | |
| SCHEMBL18885236 | 0.80 | GAA (0.33) | — | |
| SCHEMBL27281638 | 0.80 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567195-B1 | DENDRIMER CONJUGATES FOR SELECTIVE SOLUBILISATION OF PROTEIN AGGREGATES | UPFRONT CHROMATOGRAPHY AS (DK) | 2010-10-27 | — | — | EP | disclosed |