Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315539 | 1.00 | HTR2A (0.34) | HTR2AHTR2CHTR2BALOX5ALDH1A1 | |
| SCHEMBL12113936 | 0.81 | SMN1; SMN2 (0.33) | ALDH1A1MAPTSMN1; SMN2MEN1PABPC1 | |
| SCHEMBL3332876 | 0.78 | HTR2C (0.36) | HTR2AHTR2CHTR2BALOX5SMN1; SMN2 | |
| SCHEMBL335894 | 0.78 | HTR2C (0.36) | HTR2AHTR2CHTR2BALOX5SMN1; SMN2 | |
| SCHEMBL335895 | 0.78 | HTR2C (0.36) | HTR2AHTR2CHTR2BALOX5SMN1; SMN2 | |
| SCHEMBL19834267 | 0.70 | TP53 (0.47) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL910104 | 0.69 | GPR84 (0.35) | HTR2AHTR2CHTR2BALDH1A1HTT | |
| SCHEMBL15850929 | 0.63 | CYP1A2 (0.53) | ALDH1A1MEN1KMT2AMAPK1CASP1 | |
| SCHEMBL1312540 | 0.62 | DDB1 (0.41) | HTR2AHTR2CHTR2BALOX5KMT2A | |
| SCHEMBL909971 | 0.59 | KCNH2 (0.51) | ALDH1A1MEN1KMT2AMAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275661-A1 | TRICYCLIC NITROGEN COMPOUNDS USED AS ANTIBACTERIALS | GLAXO GROUP LIMITED | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275661-A1 | TRICYCLIC NITROGEN COMPOUNDS USED AS ANTIBACTERIALS | NRDC, NGLY1, NISCH | HTR2A 2784/4885HTR2C 1693/4885HTR2B 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.