SCHEMBL1315684

SCHEMBL1315684

CC(CO)OC(=O)/C=C\C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.63
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 3/20 0.38
GAA P10253 1/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
GABRP O00591 2/20 0.35
GABRD O14764 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRB1 P18505 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35
GABRA2 P47869 2/20 0.35
GABRB2 P47870 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4595947 1.00 HCAR2 (0.63) HCAR2ALDH1A1TDP1KDM4EMAPT
SCHEMBL11673309 1.00 HCAR2 (0.63) HCAR2ALDH1A1TDP1KDM4EMAPT
SCHEMBL1043266 0.91 HCAR2 (0.48) HCAR2TSHR
Maleic Acid SCHEMBL27609744 0.86 HCAR2 (0.47) HCAR2ALDH1A1TDP1KDM4EMAPT
SCHEMBL5848513 0.83 HCAR2 (0.63) HCAR2ALDH1A1TSHRGAATP53
SCHEMBL451816 0.83 HCAR2 (0.63) HCAR2ALDH1A1TDP1KDM4EMAPT
SCHEMBL1832224 0.83 HCAR2 (0.63) HCAR2ALDH1A1TDP1KDM4EMAPT
SCHEMBL1579344 0.83 HCAR2 (0.63) HCAR2ALDH1A1TDP1KDM4EMAPT
SCHEMBL18411668 0.83 HCAR2 (0.42) HCAR2MAPTTSHR
SCHEMBL3482497 0.83 HCAR2 (0.63) HCAR2ALDH1A1TSHRGAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023231046-A1 ADAPTIVE TISSUE REGENERATION PROMOTING MATERIAL 浙江大学 2023-12-07 WO claimed
CN-116137817-A Synthesis of Poly (propylene glycol maleate-co-succinate) by Zinc-and acetic acid-mediated time-dependent reduction of Poly (propylene glycol maleate) double bonds 阿克伦大学 2023-05-19 CN claimed
CN-111587128-B Synthesis and characterization of well-defined polypropylene fumarate and polyethylene glycol block copolymers 阿克伦大学 2022-04-15 CN claimed
CN-113038974-A Star-shaped poly (propylene fumarate) copolymers for 3D printing applications 阿克伦大学 2021-06-25 CN claimed
EP-1097278-B1 COMPRESSION MOLDED DOOR ASSEMBLY TT TECHNOLOGIES INC (US) 2007-03-21 EP claimed
EP-0770007-B1 COMPRESSION MOLDED DOOR ASSEMBLY THERMA TRU CORP (US) 1999-11-17 EP claimed
US-RE36240-E HAVING MOLDED DOOR SKINS THAT INCLUDE A TEXTURED PATTERN THAT SIMULATES THE GRAIN OF NATURAL WOOD THERMA-TRU CORPORATION (US) 1999-06-29 US claimed
EP-0856500-A1 Process for repairing cracked slabs Toncelli, Dario (IT) 1998-08-05 EP claimed
EP-0770007-A4 COMPRESSION MOLDED DOOR ASSEMBLY THERMA TRU CORP (US) 1997-11-19 EP claimed
EP-0770007-A1 COMPRESSION MOLDED DOOR ASSEMBLY THERMA-TRU CORP. (US) 1997-05-02 EP claimed
US-5537789-A Compression molded door assembly THERMA-TRU CORP. (US) 1996-07-23 US claimed
WO-1996002395-A1 COMPRESSION MOLDED DOOR ASSEMBLY THERMA-TRU CORP. (US) 1996-02-01 WO claimed
US-4880872-A POLYUREAS, POLYURETHANES ICI AMERICAS INC. (US) 1989-11-14 US claimed
CN-119080989-A Resin polymer, photosensitive resin composition and application thereof 常州强力先端电子材料有限公司 2024-12-06 CN disclosed
CN-115260542-B Preparation method of degradable polymer/starch master batch 湖北宜化降解新材料有限公司 2024-10-29 CN disclosed
CN-115124827-B Preparation method of degradable polymer/calcium carbonate master batch 三峡大学 2023-08-29 CN disclosed
US-4055613-A Production of three-dimensional designs AKROSIL CORPORATION (US) 1977-10-25 US disclosed
US-4000358-A ACRYLIC POLYMERSAMIDE ALELIO GAETANO F D 1976-12-28 US disclosed
US-3954714-A Polymerizable urethane compounds and polymers thereof ICI UNITED STATES INC. (US) 1976-05-04 US disclosed
US-3950392-A FIREPROOFING, HOMOPOLYMERIZATION, COPOLYMERIZATION ALELIO GAETANO F D 1976-04-13 US disclosed