SCHEMBL451816

SCHEMBL451816

CCC(C)OC(=O)C=CC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 0.63
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
GABRP O00591 2/20 0.35
GABRD O14764 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRB1 P18505 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35
GABRA2 P47869 2/20 0.35
GABRB2 P47870 2/20 0.35
GABRA4 P48169 2/20 0.35
GABRE P78334 2/20 0.35
GABRA6 Q16445 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL7565352 1.00 HCAR2 (0.63) HCAR2TSHRALDH1A1GAATP53
SCHEMBL1832224 1.00 HCAR2 (0.63) HCAR2TSHRALDH1A1GAATP53
Fumaric Acid SCHEMBL7565361 1.00 HCAR2 (0.63) HCAR2TSHRALDH1A1GAATP53
SCHEMBL1579344 1.00 HCAR2 (0.63) HCAR2TSHRALDH1A1GAATP53
Propane SCHEMBL8092488 0.98 HCAR2 (0.61) HCAR2TSHRALDH1A1GAATP53
SCHEMBL11838586 0.94 HCAR2 (0.57) HCAR2TSHRALDH1A1GAATP53
SCHEMBL510760 0.91 HCAR2 (0.48) HCAR2TSHRMAPTATM
SCHEMBL510759 0.91 HCAR2 (0.48) HCAR2TSHRMAPTATM
SCHEMBL1062134 0.91 HCAR2 (0.48) HCAR2TSHRMAPTATM
SCHEMBL21767949 0.91 HCAR2 (0.53) HCAR2TSHRALDH1A1GAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 771 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510831-B Water-dispersible polyaspartic acid ester resin, water-based automobile finishing varnish, and preparation methods and applications thereof 南京维新高分子科技有限公司 2025-03-28 CN claimed
CN-118027407-B Fluorine-silicon modified polyaspartic acid polyurea coating and preparation method thereof 南京维新高分子科技有限公司 2025-02-14 CN claimed
US-12139679-B2 Lubricity modifier for fuels and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-11-12 US claimed
CN-114230976-B Thermosetting resin composition and preparation method thereof 上海中化科技有限公司 2024-08-06 CN claimed
CN-117820954-B Water-based acrylic polyurethane finish paint and preparation method thereof 山东中胜涂料有限公司 2024-05-28 CN claimed
CN-118027407-A Fluorine-silicon modified polyaspartic acid polyurea coating and preparation method thereof 南京维新高分子科技有限公司 2024-05-14 CN claimed
CN-117820954-A Water-based acrylic polyurethane finish paint and preparation method thereof 山东中胜涂料有限公司 2024-04-05 CN claimed
CN-117510831-A Water-dispersible polyaspartic acid ester resin, water-based automobile finishing varnish, and preparation methods and applications thereof 南京维新高分子科技有限公司 2024-02-06 CN claimed
CN-109467571-B Siloxane modified aspartic acid ester and preparation method and application thereof 万华化学集团股份有限公司 2023-12-19 CN claimed
CN-116425926-A Low-surface tension type polycarboxylate superplasticizer and preparation method thereof 河北合众建材有限公司 2023-07-14 CN claimed
US-4196112-A ADDUCT OF A BUTADIENE POLYMER AN A,B-ACID, A CARBOCYCLIC ALCOHOL GELATION INHIBITOR, A HYDROPHILIC SOLVENT, A NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1980-04-01 US claimed
US-4196113-A ADDUCT OF A BUTADIENE POLYMER AND AN A,B-ACID, A 1,2-DIHYDROQUINOLINE GELATING INHIBITOR, A HYDROPHILIC SOLVENT, A NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1980-04-01 US claimed
US-4176109-A CORROSION RESISTANCE, IMPACT RESISTANCE, ADHESIONN; ADDUCT OF BUTAC SOLVENT, NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1979-11-27 US claimed
US-4175068-A ADDUCT OF BUTADIENE AND UNSATURATED DICARBOXYLIC ACID, NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1979-11-20 US claimed
US-4171308-A ADDUCT OF A BUTADIENE POLYMER AND AN A,B-UNSATURATED CARBOXY ACID COMPOUND, NEUTRALIZED NIPPON OIL CO. LTD. (JP) 1979-10-16 US claimed
US-4145501-A ADDUCT OF A LOW MOLECULAR WEIGHT BUTADIENE POLYMER AND AN UNSATURATED DICARBOXYLIC ACID COMPOUND, CORROSION RESISTANT, ADHESION, IMPACT RESISTANT NIPPON OIL CO., LTD. (JP) 1979-03-20 US claimed
US-4010174-A Thiazolinone-(2)-carboxylic acid esters and process therefor BAYER AKTIENGESELLSCHAFT (DT) 1977-03-01 US claimed
US-3990980-A Hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed
US-3991226-A Method of creating an image using hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed
US-3952023-A Method for preparing adduct of butadiene polymer or copolymer and α, β-ethylenically unsaturated dicarboxylic acid compound NIPPON OIL COMPANY LTD. (JA) 1976-04-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139679-B2 Lubricity modifier for fuels and application thereof F12, ACADM, ADH1A HCAR2 341/4885TSHR 3500/4885ALDH1A1 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.