Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.77 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729824 | 1.00 | AR (0.77) | ARPGRCYP3A4 | |
| SCHEMBL17875292 | 0.90 | AR (0.76) | ARPGRCYP3A4 | |
| SCHEMBL12729813 | 0.90 | AR (0.76) | ARPGRCYP3A4 | |
| SCHEMBL12392856 | 0.90 | AR (0.76) | ARPGRCYP3A4 | |
| SCHEMBL12729836 | 0.89 | AR (0.73) | AR | |
| SCHEMBL12729461 | 0.88 | AR (0.77) | AR | |
| SCHEMBL12707474 | 0.88 | AR (0.59) | AR | |
| SCHEMBL2746561 | 0.87 | AR (1.00) | AR | |
| SCHEMBL14086825 | 0.87 | AR (1.00) | AR | |
| SCHEMBL3698441 | 0.87 | AR (1.00) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803970-B2 | Multi-substitued selective androgen receptor modulators and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2010-09-28 | — | — | US | disclosed |
| US-7803970-B2 | Multi-substitued selective androgen receptor modulators and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2010-09-28 | — | — | US | disclosed |