Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746561 | 1.00 | AR (1.00) | AR | |
| SCHEMBL14086825 | 1.00 | AR (1.00) | AR | |
| SCHEMBL12706742 | 0.92 | AR (0.85) | AR | |
| SCHEMBL14252926 | 0.92 | AR (0.85) | AR | |
| SCHEMBL12453355 | 0.91 | AR (0.83) | AR | |
| SCHEMBL10364518 | 0.91 | AR (0.83) | AR | |
| SCHEMBL2689756 | 0.91 | AR (1.00) | AR | |
| SCHEMBL16871452 | 0.91 | AR (1.00) | AR | |
| SCHEMBL12451560 | 0.91 | AR (0.83) | AR | |
| SCHEMBL14086827 | 0.91 | AR (0.83) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276496-B1 | THERAPEUTIC MODULATION OF OCULAR SURFACE LUBRICATION | UNIV CALIFORNIA (US) | 2019-07-10 | — | — | EP | claimed |
| US-9138457-B2 | Therapeutic modulation of ocular surface lubrication | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-22 | — | — | US | claimed |
| WO-2009137602-A1 | THERAPEUTIC MODULATION OF OCULAR SURFACE LUBRICATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-11-12 | — | — | WO | claimed |
| WO-2020160452-A1 | COMBINING SERMS, SARMS, AND CANNABINOIDS FOR IMPROVING SAFETY AND EFFICACY OF ENDOCRINE THERAPIES | TESS VENTURES, INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| EP-2276497-B1 | OPHTHALMIC DEVICE, AND METHOD OF USE THEREOF, FOR INCREASING OCULAR BOUNDARY LUBRICATION | UNIV CALIFORNIA (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-2276496-B1 | THERAPEUTIC MODULATION OF OCULAR SURFACE LUBRICATION | UNIV CALIFORNIA (US) | 2019-07-10 | — | — | EP | disclosed |
| EP-2464375-B1 | PRG4 TREATMENT FOR INTERSTITIAL CYSTITIS | LUBRIS LLC (US) | 2017-06-14 | — | — | EP | disclosed |
| US-9138457-B2 | Therapeutic modulation of ocular surface lubrication | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-22 | — | — | US | disclosed |
| US-9107885-B2 | PRG4 treatment for interstitial cystitis | LUBRIS LLC (US) | 2015-08-18 | — | — | US | disclosed |
| US-8980840-B2 | Therapeutic modulation of vaginal epithelium boundary lubrication | SCHEPENS EYE RESEARCH INSTITUTE (US) | 2015-03-17 | — | — | US | disclosed |
| US-8945604-B2 | Ophthalmic device, and method of use thereof, for increasing ocular boundary lubrication | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-03 | — | — | US | disclosed |
| EP-2381957-B1 | THERAPEUTIC MODULATION OF VAGINAL EPITHELIUM BOUNDARY LUBRICATION | LUBRIS LLC (US) | 2015-01-07 | — | — | EP | disclosed |
| US-20140099343-A1 | Ophthalmic Device, and Method of Use Thereof, for Increasing Ocular Boundary Lubrication | SCHEPENS EYE RESEARCH INSTITUTE (US) | 2014-04-10 | — | — | US | disclosed |
| US-8563028-B2 | Ophthalmic device, and method of use thereof, for increasing ocular boundary lubrication | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120321693-A1 | PRG4 TREATMENT FOR INTERSTITIAL CYSTITIS | LUBRIS LLC | 2012-12-20 | — | — | US | disclosed |
| EP-2464375-A2 | PRG4 TREATMENT FOR INTERSTITIAL CYSTITIS | Singularis Inc. (US) | 2012-06-20 | — | — | EP | disclosed |
| CN-102438645-A | Therapeutic modulation of vaginal epithelial interfacial lubrication | SINGULARIS INC | 2012-05-02 | — | — | CN | disclosed |
| WO-2010083239-A2 | THERAPEUTIC MODULATION OF VAGINAL EPITHELIUM BOUNDARY LUBRICATION | TRUITT EDWARD R III (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2009137602-A1 | THERAPEUTIC MODULATION OF OCULAR SURFACE LUBRICATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009137603-A1 | OPHTHALMIC DEVICE, AND METHOD OF USE THEREOF, FOR INCREASING OCULAR BOUNDARY LUBRICATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-11-12 | — | — | WO | disclosed |