Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060103 | 0.93 | SIRT6 (0.50) | SIRT6TMEM97DRD2MAPTSERPINE1 | |
| SCHEMBL12043295 | 0.91 | SIRT6 (0.52) | SIRT6TMEM97DRD2DRD3MAPT | |
| SCHEMBL12043244 | 0.87 | SIRT6 (0.54) | SIRT6TMEM97DRD2DRD3MAPT | |
| SCHEMBL12043268 | 0.83 | SIRT6 (0.51) | SIRT6TMEM97DRD2DRD3SERPINE1 | |
| SCHEMBL13158545 | 0.83 | AR (0.46) | DRD2DRD3 | |
| SCHEMBL9984436 | 0.83 | SIRT6 (0.51) | SIRT6TMEM97DRD2DRD3SERPINE1 | |
| SCHEMBL12059676 | 0.83 | SIRT6 (0.51) | SIRT6TMEM97DRD2MAPTLMNA | |
| SCHEMBL12043264 | 0.83 | SIRT6 (0.50) | SIRT6TMEM97DRD2DRD3MAPT | |
| SCHEMBL12059471 | 0.82 | SIRT6 (0.50) | SIRT6DRD2DRD3MAPTLMNA | |
| SCHEMBL12043776 | 0.80 | SIRT6 (0.44) | SIRT6TMEM97DRD2DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115688-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-10-14 | — | — | WO | disclosed |