SCHEMBL131600

SCHEMBL131600

[CH2]C(C)(C)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5647205 0.80
Hydrochloric Acid SCHEMBL7362096 0.76
SCHEMBL5655160 0.73
SCHEMBL5921891 0.73
SCHEMBL1801978 0.70
SCHEMBL8986723 0.70
SCHEMBL9668880 0.70
SCHEMBL477927 0.67
SCHEMBL8679785 0.67 ALDH1A1 (1.00)
SCHEMBL6223 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3740481-B1 DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS CYTOKINETICS INC (US) 2024-06-26 EP claimed
WO-2024099337-A1 THIADIAZOLYL DERIVATIVES, COMPOSITIONS, AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2024-05-16 WO claimed
US-20240116956-A1 HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2024-04-11 US claimed
US-20240092790-A1 DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-03-21 US claimed
US-11897904-B2 Herbicidally active bicyclic benzamides BAYER AKTIENGESELLSCHAFT (DE) 2024-02-13 US claimed
EP-3713417-B1 HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES BAYER AG (DE) 2024-01-17 EP claimed
EP-3760193-B9 INTRACELLULAR DELIVERY VEHICLE KIRIN HOLDINGS KK (JP) 2023-11-01 EP claimed
EP-4263548-A1 DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2023-10-25 EP claimed
CN-113214422-B intracellular delivery vehicles 麒麟控股株式会社 2023-10-10 CN claimed
US-20230278996-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE S.A. (PL) 2023-09-07 US claimed
WO-2004052858-A2 INHIBITORS OF MONOAMINE UPTAKE ELI LILLY AND COMPANY (US) 2004-06-24 WO claimed
US-6605590-B1 Essential amino acids, nutrients, oligopeptides NOVUS INTERNATIONAL, INC. 2003-08-12 US claimed
EP-0891331-A1 N-(2 OXOACETYL OR SULPHONYL)-PYRROLIDINE/PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY Vertex Pharmaceuticals Incorporated (US) 1999-01-20 EP claimed
WO-1997036869-A1 N-(2 OXOACETYL OR SULPHONYL)-PYRROLIDINE/PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY VERTEX PHARMACEUTICALS INCORPORATED (US) 1997-10-09 WO claimed
US-5534536-A INHIBITORS OF THROMBOXANE A2 SYNTHETASE, 5-LIPOXYGENASE; SCAVENGERS OF ACTIVE OXYGEN SPECIES ONO PHARMACEUTICALS CO. LTD. (JP) 1996-07-09 US claimed
EP-0640609-A1 Fused phenol derivatives having inhibitory activity on TXA2 synthetase, and 5-lipoxygenase and scavenging activity on oxygen species ONO PHARMACEUTICAL CO., LTD. (JP) 1995-03-01 EP claimed
US-4467118-A PALLADIUM PHOSPHINE COMPLEX AND WEAK ACID GIVAUDAN CORPORATION (US) 1984-08-21 US claimed
EP-0094739-A1 Novel azocarboxylic esters useful as polymerisation initiators and process for their manufacture IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-23 EP claimed
EP-0080276-A1 Azocarboxylic esters useful as polymerisation initiators IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-06-01 EP claimed
EP-0080275-A1 Preparation of azoiminoether hydrochlorides from azonitriles and their hydrolysis to azocarboxylic esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-06-01 EP claimed