Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.51 |
| ▸ | PGR | P06401 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426864 | 0.88 | NR3C1 (0.53) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3426677 | 0.86 | NR3C1 (0.53) | NR3C1NR3C2PGRCYP3A4PRMT5 | |
| SCHEMBL3426216 | 0.83 | NR3C1 (0.53) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3422129 | 0.81 | NR3C1 (0.53) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3429584 | 0.75 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3424918 | 0.71 | NR3C1 (0.55) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3424774 | 0.70 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL3428026 | 0.70 | NR3C1 (0.54) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3428653 | 0.70 | NR3C1 (0.56) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3424798 | 0.69 | NR3C1 (0.56) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795272-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICAL, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-7795272-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICAL, INC. (US) | 2010-09-14 | — | — | US | disclosed |